Degree Type
Thesis
Date of Award
2012
Degree Name
Master of Science
Department
Food Science and Human Nutrition
First Advisor
Christina Campbell
Abstract
The purpose of this project was to observe whether consuming a DHA supplement with or without a meal influenced the bioavailability of the DHA supplement. Healthy males (n = 109) aged 18-45 years were randomized to 4 study groups that included 200 mg/d DHA consumed with a meal, 200 mg/d DHA consumed fasted, 1000 mg/d DHA consumed with a meal or 1000 mg/d DHA consumed in a fasted state over 8 weeks. Fasted venous blood samples were collected pre- and post-DHA supplementation for analysis of plasma phospholipid (PL) fatty acid analysis. Plasma PL DHA increased significantly in all groups (P < 0.0001). The increase in DHA was significantly different between all dose groups (200 mg versus 1000 mg; P < 0.0001). There were no differences between the meal or fasted groups. Thus, consuming a DHA supplement with a meal did not increase the bioavailability of the DHA supplement.
Copyright Owner
Stephanie J Kratzer
Copyright Date
2012
Language
en
File Format
application/pdf
File Size
100 pages
Recommended Citation
Kratzer, Stephanie J., "Influence of food on the bioavailability of a docosahexaenoic acid supplement" (2012). Graduate Theses and Dissertations. 12869.
https://lib.dr.iastate.edu/etd/12869
