Degree Type

Thesis

Date of Award

2012

Degree Name

Master of Science

Department

Food Science and Human Nutrition

First Advisor

Christina Campbell

Abstract

The purpose of this project was to observe whether consuming a DHA supplement with or without a meal influenced the bioavailability of the DHA supplement. Healthy males (n = 109) aged 18-45 years were randomized to 4 study groups that included 200 mg/d DHA consumed with a meal, 200 mg/d DHA consumed fasted, 1000 mg/d DHA consumed with a meal or 1000 mg/d DHA consumed in a fasted state over 8 weeks. Fasted venous blood samples were collected pre- and post-DHA supplementation for analysis of plasma phospholipid (PL) fatty acid analysis. Plasma PL DHA increased significantly in all groups (P < 0.0001). The increase in DHA was significantly different between all dose groups (200 mg versus 1000 mg; P < 0.0001). There were no differences between the meal or fasted groups. Thus, consuming a DHA supplement with a meal did not increase the bioavailability of the DHA supplement.

Copyright Owner

Stephanie J Kratzer

Language

en

File Format

application/pdf

File Size

100 pages

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