Date of Award
Master of Science
Veterinary Microbiology and Preventive Medicine
James A. Roth
Michael B. Roof
Porcine reproductive and respiratory syndrome virus continues to be a significant problem for pork producers. The aim of this body of work was to help stakeholders control and prevention infection with this virus. A literature review of currently available diagnostic tests and guidelines for their interpretation serves as a resource for producers, practitioners, and researchers. The research focus was to evaluate two novel methods to develop improved modified live vaccines. The efficacy of viral chimeras constructed from a commercially available vaccine and a virulent wild-type isolate and the ability to attenuate wild-type isolates with a unique cell passage process are reported. Both techniques proved to be capable of developing potential vaccine candidates.
Joshua Scott Ellingson
Ellingson, Joshua Scott, "Porcine Reproductive and Respiratory Syndrome Virus: Diagnostic update and search for novel modified live vaccines" (2013). Graduate Theses and Dissertations. 13006.