Degree Type

Thesis

Date of Award

2013

Degree Name

Master of Science

Department

Veterinary Microbiology and Preventive Medicine

First Advisor

James A. Roth

Second Advisor

Michael B. Roof

Abstract

Porcine reproductive and respiratory syndrome virus continues to be a significant problem for pork producers. The aim of this body of work was to help stakeholders control and prevention infection with this virus. A literature review of currently available diagnostic tests and guidelines for their interpretation serves as a resource for producers, practitioners, and researchers. The research focus was to evaluate two novel methods to develop improved modified live vaccines. The efficacy of viral chimeras constructed from a commercially available vaccine and a virulent wild-type isolate and the ability to attenuate wild-type isolates with a unique cell passage process are reported. Both techniques proved to be capable of developing potential vaccine candidates.

DOI

https://doi.org/10.31274/etd-180810-3363

Copyright Owner

Joshua Scott Ellingson

Language

en

File Format

application/pdf

File Size

132 pages

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