Date of Award
Doctor of Philosophy
Parkinson's disease (PD) is a neurodegenerative disorder in which the substantia nigra has suffered a severe amount of cell loss, resulting in basal ganglia dysfunction. The defining motor symptoms of PD are tremor, rigidity (stiffness of the limbs and trunk), bradykinesia (slow movements), and postural instability (impaired balance). Persons with PD also have a number of non-motor symptoms such as anxiety, depression, autonomic dysfunction, cognitive impairment, and deficits in sensory processing. Currently, there is a gap in our knowledge about how stress affects persons with PD. Anecdotally, many people with PD report that their symptoms get worse when they are stressed. However, there is only indirect and anecdotal evidence for persons with PD. Thus, the purpose of this study was to examine how stress affects motor and non-motor symptoms in persons with PD.
Zaman, Andrew, "The effects of stress on working memory, inhibitory gating, and motor symptoms in Parkinson’s disease" (2020). Graduate Theses and Dissertations. 18253.