Cultivation of hop plants in the United States dates back to 1633 when the first brewery was opened by Dutch immigrants near Fort Amsterdam on the southern tip of Manhattan Island, New York. Although the primary use for hop cones is flavoring and preservation of beer, research is ongoing for further uses of hop cones and resins as a sedative and antibacterial and antifungal properties.
Takle, Bryn and Cochran, Diana
"Evaluating the Effects of Nitrogen Fertilization on Hop Yield,"
Farm Progress Reports: Vol. 2016
, Article 28.
Available at: https://lib.dr.iastate.edu/farmprogressreports/vol2016/iss1/28