Campus Units

Genetics, Development and Cell Biology, Agronomy, Center for Metabolic Biology

Document Type

Article

Publication Version

Submitted Manuscript

Publication Date

2-19-2019

Journal or Book Title

bioRxiv

DOI

10.1101/554501

Abstract

Ortholog inference is a key step in understanding the evolution and function of a gene or other genomic feature. Yet often no similar sequence can be identified, or the true ortholog is hidden among false positives. A solution is to consider the sequence's genomic context. We present the generic program, synder, for tracing features of interest between genomes based on a synteny map. This approach narrows genomic search-space independently of the sequence of the feature of interest. We illustrate the utility of synder by finding orthologs for the Arabidopsis thaliana 13-member gene family of Nuclear Factor YC transcription factor across the Brassicaceae clade.

Comments

This is a pre-print made available through bioRxiv at doi: 10.1101/554501.

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Copyright Owner

Author/Funder

Language

en

File Format

application/pdf

Published Version

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