Campus Units
Genetics, Development and Cell Biology
Document Type
Article
Publication Version
Published Version
Publication Date
1-2018
Journal or Book Title
Plant Physiology
Volume
176
First Page
219
Last Page
229
DOI
10.1104/pp.17.01236
Abstract
Autophagy, literally defined as “self-eating,” functions as a degradation process by recycling cytoplasmic contents under stress conditions or during development. Upon activation of autophagy, a membrane structure known as a phagophore forms and expands, finally closing to form a double-membrane vesicle called an autophagosome (Fig. 1; Lamb et al., 2013; Yin et al., 2016). The completed autophagosome, which contains the autophagic cargo, is delivered to the vacuole (plants and yeast) or lysosome (animals). The outer membrane fuses with the vacuolar/lysosomal membrane, and the inner membrane and contents are released into the vacuole/lysosome as an autophagic body and are degraded by hydrolases. The breakdown products are transported back into the cytoplasm for reuse by the cell (Yang and Bassham, 2015).
Copyright Owner
American Society of Plant Biologists
Copyright Date
2018
Language
en
File Format
application/pdf
Recommended Citation
Soto-Burgos, Junmarie; Zhuang, Xiaohong; Jiang, Liwen; and Bassham, Diane C., "Dynamics of Autophagosome Formation" (2018). Genetics, Development and Cell Biology Publications. 219.
https://lib.dr.iastate.edu/gdcb_las_pubs/219
Included in
Cell Biology Commons, Developmental Biology Commons, Genetics Commons, Plant Biology Commons
Comments
This article is published as Soto-Burgos J, Zhuang X, Jiang L, Bassham DC. Dynamics of Autophagosome Formation. Plant physiology. 2018; 176:219-229. doi: 10.1104/pp.17.01236. Copyright American Society of Plant Biologists. Posted with permission.