Using LabView for Signal Processing and Noise Reduction for Flow Cytometry

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Date
2016-04-27
Authors
Feddersen, Jacob
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Honors Projects and Posters
University Honors Program

The Honors project is potentially the most valuable component of an Honors education. Typically Honors students choose to do their projects in their area of study, but some will pick a topic of interest unrelated to their major.

The Honors Program requires that the project be presented at a poster presentation event. Poster presentations are held each semester. Most students present during their senior year, but may do so earlier if their honors project has been completed.

This site presents project descriptions and selected posters for Honors projects completed since the Fall 2015 semester.

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Electrical and Computer Engineering
Abstract

Flow cytometry is a method by which microparticles and cells in a stream of fluid can be measured. Most currently available cytometers are very large and expensive because they require equipment such as lasers and optics. Our goal was to create a basic lightweight, inexpensive cytometer. The sensor works by passing the fluid with the particles through a specially designed microchannel that forces the particles to flow through in single file. The particles are measured by taking into account their optical properties; an LED of a specific frequency is shined on the particles which excites them, causing them to emit light of another specific frequency. This light can then be measured to detect the particles. Currently, the system is built and operational but suffers from excessive electrical noise. To mitigate the noise, we have used shielding to eliminate as much external interference as possible. In addition, we implemented data filtering in LabView to further reduce noise. Although these measures have drastic...

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