Nitrate from fertilizers and manure application have been detected in the surface and ground water in many agricultural regions of the country including Iowa. The current practices of fertilizer application methods and rates are believed to be contributing significantly in the contamination of groundwater. Therefore, it is imperative that tillage and planting systems, regarded as best management practices for agricultural sustainability, minimize the potential for chemical runoff and leaching losses to groundwater with alternative chemical management systems. If the potential for contamination is not reduced by developing and successfully demonstrating the innovative nitrogen and pesticide management practices, the potential for contamination will remain and could result in additional regulations. Because of these concerns, researchers must develop alternative farming practices with the goals of reducing the input costs, and preserving the resource base for the sustainability of our agriculture and protecting the environment.