Presenter Information

Peter Goldsbrough, Purdue University

Start Date

1-12-2016 12:00 AM

Description

In 1994 the Flavr Savr tomato was the first transgenic plant to be grown commercially in the United States. These tomatoes were developed by Calgene to have improved taste and longer shelf life compared to the conventional tomatoes available in the supermarket at that time. The ripening process was altered by silencing a gene using “antisense RNA”. The scientists who developed the Flavr Savr tomato, and many other biotechnologists who were attempting to modify plants at that time, did not understand the details of how antisense RNA functioned. It would take a few more years before the mechanism was elucidated and for this Andrew Fire and Craig Mello were awarded the Nobel Prize in 2006. The antisense RNA produced in the Flavr Savr tomato inadvertently tapped into a mechanism called RNA interference that is used by plants and animals to control the expression of genes.

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Dec 1st, 12:00 AM

Is RNA interference the next big thing in crop protection?

In 1994 the Flavr Savr tomato was the first transgenic plant to be grown commercially in the United States. These tomatoes were developed by Calgene to have improved taste and longer shelf life compared to the conventional tomatoes available in the supermarket at that time. The ripening process was altered by silencing a gene using “antisense RNA”. The scientists who developed the Flavr Savr tomato, and many other biotechnologists who were attempting to modify plants at that time, did not understand the details of how antisense RNA functioned. It would take a few more years before the mechanism was elucidated and for this Andrew Fire and Craig Mello were awarded the Nobel Prize in 2006. The antisense RNA produced in the Flavr Savr tomato inadvertently tapped into a mechanism called RNA interference that is used by plants and animals to control the expression of genes.

 

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