Two Recent Developments Veterinary Therapeutics
Date
1950
Authors
Austin, James
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Iowa State University Digital Repository
Abstract
In 1902 the term anaphylaxis was coined to describe a condition observed in animals and in 1904 Theobald Smith made the important observation that guinea pigs could be easily sensitized and thus provided a laboratory animal for experimental use. In 1910 Barger & Dale isolated histamine from ergot and Dale was led to believe that the pharmacological effects of histamine in animals resembled those seen in anaphylactic shock.