A wide variety of infections is found in the clinical material submitted to the Veterinary Clinic at Iowa State College. Some of these infections are relatively easy to control by pharmaceutic, biologic or antibiotic agents, by surgical procedures or by combinations of these methods. Other types of infection have proved themselves to be stubbornly resistant to such agents and methods as have hereto- fore been available to the clinician. An organism belonging near the head of this list is Corynebacterium pyogenes. Short of surgical amputation of infected parts little benefit could be obtained by methods of treatment known up to the present time. This organism localized in nearly any organ, structure or part of the body, especially in bovines, having been found from the feet to the brain of cattle autopsied at the Veterinary Clinic post mortem laboratory.