With the advent of several new anthelmintic discoveries in the past few years the treatment of the various helmiths of domestic animals has taken on new aspects. The problem of parasites and parasite control is not new. yet, with the ever increasing stress placed on our animals for faster and more economical gains and for greater milk production, the parasitic problem takes on greater significance. It is hoped that a brief discussion of the various anthemithics and the overall parasite problem will enable the practitioners to handle this problem more effectively.