Azoturia, also known as paralytic myoglobinuria and paralytic myohemoglobinemia is a disease of the equine, occurring during exercise, after a period of inactivity, while on full rations. The primary lesion noted is muscle degeneration resulting in release of myoglobin into the blood plasma. This circulating myoglobin is filtered into the urine by the kidneys resulting in clinical signs of myoglobinuria. Secondary lesions involving the kidneys result from their increased filtration of myoglobin, this clouding the clinical picture of this disease.