The role of veterinary medicine in the United States food animal industry is currently changing. Veterinarians are no longer viewed as mere providers of clinical services such as healing individual sick animals. This traditional role is being replaced with planned animal health programs for the entire herd. The objective of production medicine is to consistently maintain overall animal health and increase production cost-effectively to attain optimum economic returns for the producer. This holistic approach to animal health and production reduces the importance of specific infectious agents per se, and concentrates on the effect of interactions of these agents, environment, nutrition, genetics, and management on animal performance. Attempting to assimilate all these factors, in hopes of developing specific recommendations for the producer, may seem overwhelming when starting a production medicine program. This case report will illustrate the diagnostic procedures used to evaluate these factors when initiating a program for a swine herd in central Iowa.