A method of decreasing plasma cholesterol is disclosed. The method includes oral administration of coprostanol-producing bacteria to humans. These organisms, once in the small intestine, will reduce free cholesterol to coprostanol, which is absorbed poorly. Pharmaceutical compositions for delivery are included as are different methods of delivery such as placing the microorganisms in food.
ISURF Reference Number
Iowa State University Research Foundation, Inc.,
Beitz, Donald C.; Young, Jerry W.; Li, Ling; and Buhman, Kimberly K., "Oral administration of coprostanol producing microorganisms to humans to decrease plasma cholesterol concentration" (1995). Iowa State University Patents. 150.