A method of testing serum from swine vaccinated against pseudorabies virus with viral envelope-based subunit vaccines to determine the presence of antibodies to infecting pseudorabies virus in wihch an immunoassay is performed on the swine serum using a pseudorabies virus antigen preparation comprising nucleocapsid proteins of the pseudorabies virus. The universal diagnostic antigen is one or more nucleocapsid proteins having relative molecular weights of approximately 23 k, 34 k, 41 k, 63 k and 140 k.
ISURF Reference Number
Iowa State University Research Foundation, Inc.,
McGinley, Michael J. and Platt, Kenneth B., "Method of detecting pseudorabies virus specific serum antibody by use of a universal diagnostic antigen" (1992). Iowa State University Patents. 238.