A positive pressure long-term drug delivery device particularly useful for the intravaginal or intrauterine release of a drug capable of passing through a diffusion membrane and being absorbed by the vaginal or uterine epithelium. The device includes a tubular casing having a plunger urged by a compression spring to create a continuous positive pressure on a drug in liquid form within the chamber of the casing, a supported membrane at one end of the casing through which such drug diffuses at a predetermined rate, and resilient elements at the opposite end of the casing for facilitating retention of the device throughout the term of administration of the drug.
ISURF Reference Number
Iowa State University Research Foundation, Inc.,
Magoon, Keith E.; Evans, Lawrence E.; and Hembrough, Frederick B., "Positive pressure drug releasing device" (1982). Iowa State University Patents. 239.