A method for determining muscle mass in a human subject useful for monitoring athletic conditioning, weight loss programs, nutritional deficiencies, and disease states which cause muscle wasting is provided comprising administration of a bolus dose of a metabolic marker for 3-methylhistidine, the use of a three-compartment model to describe data from blood samples collected periodically thereafter, and calculation of muscle mass as a function of specific values generated by the model.
Iowa State University Research Foundation, Inc.
Nissen, Steven L.; Rathmacher, John A.; and Flakoll, Paul J., "Method for measuring muscle mass" (1997). Iowa State University Patents. 43.