A composition is provided that inhibits DNA replication in activated cell-free extracts of Xenopus eggs, which is prepared by a process comprising subjecting homogenates of Xenopus ovaries to a series of chromatographic separations so as to isolate a purified fraction comprising a protein having a molecular weight ofabout 245 kDa.
Iowa State University Research Foundation, Inc.
Benbow, Robert M. and Zhao, Jiyong, "Inhibitor of chromosomal DNA replication in xenopus: the turhuter protein" (1999). Iowa State University Patents. 93.