Campus Units
Plant Pathology and Microbiology
Document Type
Article
Publication Version
Published Version
Publication Date
2017
Journal or Book Title
Nature Communications
Volume
8
First Page
14493
DOI
10.1038/ncomms14493
Abstract
Vector-borne pathogens influence host characteristics relevant to host–vector contact, increasing pathogen transmission and survival. Previously, we demonstrated that infection with Turnip mosaic virus, a member of one of the largest families of plant-infecting viruses, increases vector attraction and reproduction on infected hosts. These changes were due to a single viral protein, NIa-Pro. Here we show that NIa-Pro responds to the presence of the aphid vector during infection by relocalizing to the vacuole. Remarkably, vacuolar localization is required for NIa-Pro’s ability to enhance aphid reproduction on host plants, vacuole localization disappears when aphids are removed, and this phenomenon occurs for another potyvirus, Potato virus Y, suggesting a conserved role for the protein in vector–host interactions. Taken together, these results suggest that potyviruses dynamically respond to the presence of their vectors, promoting insect performance and transmission only when needed.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Copyright Owner
The Authors
Copyright Date
2017
Language
en
File Format
application/pdf
Recommended Citation
Bak, Aurélie; Cheung, Andrea L.; Yang, Chunling; Whitham, Steven A.; and Casteel, Clare L., "A viral protease relocalizes in the presence of the vector to promote vector performance" (2017). Plant Pathology and Microbiology Publications. 207.
https://lib.dr.iastate.edu/plantpath_pubs/207
Included in
Agricultural Science Commons, Agriculture Commons, Agronomy and Crop Sciences Commons, Plant Pathology Commons
Comments
This article is published as Bak, Aurélie, Andrea L. Cheung, Chunling Yang, Steven A. Whitham, and Clare L. Casteel. "A viral protease relocalizes in the presence of the vector to promote vector performance." Nature Communications 8 (2017): 14493. doi: 10.1038/ncomms14493. Posted with permission.