Campus Units

Plant Pathology and Microbiology

Document Type

Response or Comment

Publication Version

Accepted Manuscript

Publication Date

8-9-2019

Journal or Book Title

The FEBS journal

DOI

10.1111/febs.15022

Abstract

In unstressed conditions, the cap‐binding protein, eIF4E, binds the 5′ cap structure (m7G) on mRNA and recruits other translation initiation factors to bring the ribosome to the mRNA. Bruns et al. show that, in plants, phosphorylation of eIF4E by the master metabolic regulatory protein, sucrose nonfermenting‐related kinase 1 (SnRK1), reduces translation globally. This negative regulation of translation inhibits geminivirus infection and is speculated to be a response to various abiotic stresses.

Comments

This is the peer reviewed version of the following article: Miller, W. Allen, and Savithramma P. Dinesh‐Kumar. "A new mechanism for translational control in plants." The FEBS Journal, which has been published in final form at doi: 10.1111/febs.15022. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

Copyright Owner

Federation of European Biochemical Societies

Language

en

File Format

application/pdf

Available for download on Sunday, August 09, 2020

Published Version

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