Timed Up and Go, Cognitive, and Quality-of-Life Correlates in Parkinson’s Disease

Shelley, Mack; Nocera, Joe; Malaty, Irene; Stegemoller, Elizabeth; Hass, Chris; NPF Quality Improvement Initiative Investigators

Timed Up and Go, Cognitive, and Quality-of-Life Correlates in Parkinson’s Disease

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2014_ShelleyMack_TimedUp.pdf (627.09 KB)

Date

2014-04-01

Authors

Shelley, Mack

Nocera, Joe

Malaty, Irene

Shelley, Mack

Stegemoller, Elizabeth

Hass, Chris

NPF Quality Improvement Initiative Investigators

Authors

Person

Shelley, Mack

University Professor

Person

Stegemoller, Elizabeth

Associate Professor

Organizational Units

Organizational Unit

Political Science

The Department of Political Science has been a separate department in the College of Liberal Arts and Sciences (formerly the College of Sciences and Humanities) since 1969 and offers an undergraduate degree (B.A.) in political science, a graduate degree (M.A.) in political science, a joint J.D./M.A. degree with Drake University, an interdisciplinary degree in cyber security, and a graduate Certificate of Public Management (CPM). In addition, it provides an array of service courses for students in other majors and other colleges to satisfy general education requirements in the area of the social sciences.

Organizational Unit

Statistics

As leaders in statistical research, collaboration, and education, the Department of Statistics at Iowa State University offers students an education like no other. We are committed to our mission of developing and applying statistical methods, and proud of our award-winning students and faculty.

Department

Political ScienceStatistics

Abstract

Objective: To examine the relationship between Timed Up and Go (TUG) performance, verbal executive function (EF) performance, and quality-of-life (QOL) measures in Parkinson's disease (PD).

Design: Cross-sectional.

Setting: Sixteen movement disorder centers from across the United States.

Participants: Patients with PD (N=1964).

Interventions: Not applicable.

Main Outcome Measures: TUG test, immediate and delayed 5-word recall, verbal fluency, PD QOL Questionnaire.

Results: TUG performance and verbal EF performance were significantly associated with, and predictors of, QOL measures, having the greatest association and predictability with the mobility domain of the QOL measures.

Conclusions: The TUG test and verbal EF tests have QOL correlates, making the combined evaluation of mobility, cognitive, and QOL decline a potential examination tool to evaluate the sequelae of PD.

Comments

This article is published as Stegemöller, Elizabeth L., Joe Nocera, Irene Malaty, Mack Shelley, Michael S. Okun, Chris J. Hass, and NPF Quality Improvement Initiative Investigators. "Timed up and go, cognitive, and quality-of-life correlates in Parkinson's disease." Archives of Physical Medicine and Rehabilitation 95, no. 4 (2014): 649-655. DOI: 10.1016/j.apmr.2013.10.031.