SNARE driven membrane fusion proceeds through an unknown process of events. It is still a mystery whether there is one chronological order of events for SNARE fusion or if there are multiple pathways. Two intermediates, hemifusion and protein fusion pore, have been found. The relationship between these two intermediates are unknown. If the two are part of the same pathway, hemifusion would logically precede a fusion pore but it is unknown how the SNAREs are involved with either. By using total lipid mixing and inner lipid mixing fluorescence, syntaxin G276W, which is known to affect fusion pore stability, was compared with the wild type syntaxin during SNARE fusion. These assays showed no difference in total lipid mixing and amount of hemifusion between fusion with the wild type syntaxin and G276W syntaxin. Syntaxin G276W, which affects foot size in neurotransmitter release, does not change the SNAREs fusion rate or amount of hemifusion. This result shows that by disrupting the fusion pore size, the fusion and hemifusion rates are not effected. How the protein fusion pore is related to hemifusion in the fusion model is still a mystery.