New and Old, Modern and Tradition are always hotly debated topics today among Chinese architects. The objectives of this thesis are to find out the fundamental reasons that cause the cultural rupture between tradition and modern through thesis research and to achieve new harmony through a newly enriched design process that is inspired by the research. The thesis research consists of four parts: l, the city of Beijing; 2, scientific revolution - Thomas Kuhn; 3, Unweaving the rainbow - Richard Dawkins; 4, ancient theories - poetic solution. After a design theory is developed with the help of the thesis research, a design process has been formed by hybridizing long-lasting spirits and Zeitgeist as new poetry to achieve new harmony of our time with the help of science. A design solution of a Chinese ancient science museum is following to test this design theory by utilizing the new design process. Overall, neither the adoption of ancient theories or forms (appearance) nor abandoning history can be the way to reach the goal of this thesis. The new design process reflects how to reach this goal - finding the essence behind ancient theories and examples will lead to a new thinking on re-balancing science and poetry today. And thus new harmony between man and nature can be achieved by science as well as poetry, by "knowledge" as well as experience, by ration as well as passion.