Date of Award
Doctor of Philosophy
A direct injection nebulizer (DIN) was designed, developed, and evaluated to determine its potential utilization as an effective inter- face for flow injection analysis (FIA) and high performance liquid chromatography (HPLC) coupled with inductively coupled plasma-atomic emission spectroscopic detection. The analytical figures of merit for the DIN when used as an interface for FIA-ICP-AES were found to be comparable to or better than those obtained with conventional pneumatic nebulization in terms of limits of detection (LODs), reproducibility, linearity, and interelement effects. In the HPLC mode, the LODs were found to be comparable to those obtained by continuous-flow sample introduction into the ICP, or inferior by up to only a factor of four. Stable plasma operation was maintained for the DIN sample introduction of a variety of pure organic solvents, including acetonitrile, methanol, methyl- isobutylketone, and pyridine. The HPLC-DIN-ICP-AES facility was specifically applied for the speciation of inorganic and organo- metallic species contained in synthetic mixtures, vanilla extracts, and a variety of energy-related materials, such as shale oil process;water, coal extracts, shale oil, crude oil, and an SRC II. Suggestions for future research are also considered; ('(DAG))DOE Report IS-T-1227. This work was performed under Contract W-7405-Eng-82 with the U.S. Department of Energy.
Digital Repository @ Iowa State University, http://lib.dr.iastate.edu/
Kimberly E. LaFreniere
LaFreniere, Kimberly E., "Evaluation of a direct injection nebulizer interface for flow injection analysis and high performance liquid chromatography with inductively coupled plasma-atomic emission spectroscopic detection " (1986). Retrospective Theses and Dissertations. 8013.