Physiological effects of blood flow through a region of induced atherosclerosis in the rat with emphasis on the effect of exercise on thrombosis and collateral vessel recruitment
Date
Authors
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Altmetrics
Authors
Research Projects
Organizational Units
The function of the Department of Chemical and Biological Engineering has been to prepare students for the study and application of chemistry in industry. This focus has included preparation for employment in various industries as well as the development, design, and operation of equipment and processes within industry.Through the CBE Department, Iowa State University is nationally recognized for its initiatives in bioinformatics, biomaterials, bioproducts, metabolic/tissue engineering, multiphase computational fluid dynamics, advanced polymeric materials and nanostructured materials.
History
The Department of Chemical Engineering was founded in 1913 under the Department of Physics and Illuminating Engineering. From 1915 to 1931 it was jointly administered by the Divisions of Industrial Science and Engineering, and from 1931 onward it has been under the Division/College of Engineering. In 1928 it merged with Mining Engineering, and from 1973–1979 it merged with Nuclear Engineering. It became Chemical and Biological Engineering in 2005.
Dates of Existence
1913 - present
Historical Names
- Department of Chemical Engineering (1913–1928)
- Department of Chemical and Mining Engineering (1928–1957)
- Department of Chemical Engineering (1957–1973, 1979–2005)
- Department of Chemical and Biological Engineering (2005–present)
- College of Engineering(parent college)
Related Units
Journal Issue
Is Version Of
Versions
Series
Department
Abstract
The integrity of the anterior tibialis muscle in the rodent was investigated for conditions of normal and complete occlusion of nutrient iliac blood flow. Integrity was defined as the ability of the muscle to contract during severe ischemia. Occlusion of the iliac vessel was accomplished by mechanical ligation or thromboplastin-induced arterial thrombosis;This research examined the alteration of peripheral hemodynamics with acute vascular insufficiency in the left hind limb of the exercised and sedentary rat. The techniques presented suggest that characterization of the rodent hind limb vascular supply was possible by both hemodynamic evaluation and electromyographic analysis. The importance of vascular supply on muscle performance was demonstrated. This was correlated not only to the reactive hyperemic state of the limb but also to dynamic work capacity of the anterior tibialis muscle under induced loading as measured by the electromyogram.