Degree Type


Date of Award


Degree Name

Doctor of Philosophy


Animal Science


The utilization of glucose and sucrose by the weanling pig was evaluated in a comparative slaughter experiment. Glucose had lower gross (GE) and digestible energy (DE) than sucrose. There were no significant differences in the metabolizable (ME) and net energy (NE) values of these sugars. The energy values, in kcal/g dry matter, for glucose and sucrose respectively were: GE, 3.68, 3.96; DE, 3.43, 3.55; ME, 3.28, 3.43; NE, 2.48, 2.62. There were no differences in whole body fat or protein deposition. Sucrose fed pigs had larger hepatic glycogen stores than glucose fed pigs;In a second experiment, 10 pigs were implanted with femoral vein and arterial catheters to evaluate the effects of dietary glucose and sucrose on leucine metabolism. The glucose fed pigs had higher mean postprandial glucose and insulin concentrations. The pigs received a primed dose-constant infusion of (4,5-('3)H) leucine and (U-('14)C) (alpha)-ketoisocaproate on the day of experiment. The isotope data were analyzed using a two pool model. There were no dietary influences on net protein synthesis in the fasting state. This was in spite of greater preprandial proteolysis among glucose fed pigs. The glucose fed animals also had the highest postprandial total leucine carbon flux. Protein synthesis increased and leucine transamination decreased after consumption of the glucose meal. No such changes were found among the sucrose fed pigs. The data suggest independent control of protein synthesis and transamination activity;The combined results from these experiments suggest large differences in the way glucose and sucrose influence metabolism in the liver, adipose tissue and the hind limbs of pigs. It appears, however, that these differences do not affect the overall utilization of the glucose and sucrose based diets.



Digital Repository @ Iowa State University,

Copyright Owner

Ståle Johannes Helland



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60 pages