Date of Award
Doctor of Philosophy
Richard C. Larock
This dissertation is divided into three chapters. The first chapter deals with an unprecedented cyclization that occurs during the reaction of norbornadiene-palladium dichloride and 1-iodomercurio-2-butyne. This reaction yields two novel [sigma]-vinylpalladium compounds. The work in chapter one focuses on obtaining further support for the two proposed structures. The second chapter deals with palladium-catalyzed arylannulation of conjugated dienes. Appropriately substituted aryl iodides and 1,3-dienes undergo a one-step, palladium(0)-catalyzed reaction to furnish polycycles. During arylannulation two carbon-carbon bonds are formed under relatively mild conditions. Chapter three is an extension of the work in the second chapter. Palladium-catalyzed arylannulation of non-conjugated dienes, alkynes, and simple olefins have been examined, and polycycles are formed under relatively mild conditions.
Digital Repository @ Iowa State University, http://lib.dr.iastate.edu/
Colleen Ann Fried
Fried, Colleen Ann, "Palladium-mediated cyclizations " (1990). Retrospective Theses and Dissertations. 9367.