The Food and Drug Administration (FDA) has primary responsibility in the federal government for food safety in the United States. FDA is charged with the enforcement of the Federal Food, Drug, and Cosmetic Act (FFDCS), and food safety related aspects of the Public Health Service Act (PHSA). The FDA mandate under these Acts includes widespread responsibilities to help ensure preharvest food safety. One mission of FDA's Center for Veterinary Medicine (CVM) is to regulate the levels of contaminants permitted in animal feeds to ensure that the food for man and animals is safe and free of illegal drugs, industrial chemica. pesticide residues, and harmful bacteria. To meet this mandate, CVM has emphasized the application of HACCP programs in the feed industry as an approach for achieving salmonella negative feed. To establish a baseline in the feed industry, CVM has conuducted surveys to determine the prevalence of salmonella contamination in animal and vegetable proteins, complete feed, and the primary protein meal ingredient.