To reduce Salmonella prevalence in pork, measures should be taken throughout the pork production chain, including pigs on the farm. Epidemiological studies showed that the use of fermented feed can significantly reduce Salmonella prevalence in pigs compared to the use of normal feed. Experimental challenge experiments with Salmonella, however, have never been conducted to reveal the efficacy of fermented feed to reduce Salmonella shedding and/or reduce the number of Salmonella positive pigs. A study was conducted to measure the effect of fermented feed on Salmonella enterica serovars In this experiment seeder pigs were used as a mode for Salmonella transmission within a pig herd. The results showed that fermented feed does affect the gastrointestinal ecology (other poster/manuscript present at this symposium), but has no beneficial effect on Salmonella prevalence in pigs.