Antimicrobial resistance profile and genetic diversity of Salmonella enterica serotypes Typhimurium and Muenchen
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The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.
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The aim of this study was to compare the antimicrobial resistance pattern and genetic diversity of Salmonella enterica serotypes Typhimurium and Muenchen from human and swine. Previously, we reported two predominant multi-drug resistant (MDR) patterns common among Salmonella isolates from swine. In this study we report serovar Muenchen, to have MDR pattern similar to Typhimurium and with expanded spectrum in swine (AmCmStSuTeKm). This pattern is more frequent among isolates from swine (with 46% frequency) while most of isolates from human were pansusceptible (only one isolate with MDR to 10 antimicrobials). Genotyping using PFGE revealed swine and human isolates clustered separately from each other. We identified class-I integrons among nine S. Muenchen isolates from swine and single isolate from human using polymerase chain reaction (PCR). We propose that interserovar exchange of resistance genes might be responsible for emergence of MDR strains among serovars not previously showing MDR. Further molecular investigations are underway.