Adaptive resistance to Biocides and implications of cross-resistance to Antimicrobial Agents in Foodborne Pathogens.

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2003-01-01
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Braoudaki, M.
Hilton, A.
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International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork
Iowa State University Conferences and Symposia

The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.

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This study was focused on the potential for adaptive resistance in Salmonella and Escherichia coli to commonly used biocides, to identify resistance strategies and any cross-resistance to antibiotics. Bacteria were serially exposed in sub-inhibitory concentrations of biocides and adaptive resistance was observed in all strains investigated. Erythromycin-resistant Salm. Enteritidis did not cross-resist to biocides, whereas erythromycin-resistant Salm. Typhimurium express cross-resistance to chlorohexidine. Benzalkonium chloride-resistant Salm. Virchow showed an elevated resistance to chlorohexidine, however chlorohexidine-resistant Salm. Virchow did not demonstrate it back.

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Wed Jan 01 00:00:00 UTC 2003