Cellular immune responses in porcine reproductive and respiratory syndrome virus (PRRSV) vaccinated weaned piglets challenged with a virulent strain of PRRSV
Date
Authors
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Altmetrics
Authors
Research Projects
Organizational Units
Journal Issue
Is Version Of
Versions
Series
The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.
Department
Abstract
The porcine reproductive and respiratory syndrome (PRRS) is an important viral infection of swine that can persist in lymphoid organs of infected pigs despite the induction of specific immune responses, suggesting an immune evasion mechanism. Vaccination has been shown to prevent climcal signs but remains ineffective against viral persistence. Our objective was to investigate the immunological disorders related to vaccination and subsequent challenge by a virulent strain. Groups of piglets were vaccmated with RespPRRS vaccine (Boehringer-lngelheim) and challenged 4 weeks later with the virulent LHVA-93-3 strain of the PRRS virus.