Publication Date

January 2011

Abstract

Sanguinarine, a quaternary benzophenanthridine alkaloid plant extract of Macleya cordata, has demonstrated to have anti-inflammatory, antimicrobial and immunomodulatory effect. It increases the availability of aromatic amino acids and decreases the levels of toxic biogenic amines. This study was aimed to evaluate the effect of Sangrovit® supplementation as compared to tylosin on growth performance, feed efficiency and Lawsonia intracellularis shedding in pigs, and to determine the effect of Sangrovit® on the immune system. A total of 24 pigs, four weeks-old challenged with Lawsonia intracellularis were randomly allocated to a treatment group (control non-supplemented, 40 g Sangrovit®/mton, 75 g Sangrovit®/mton, and 22g /kg tylosin). Pigs were weighed weekly and average daily gain (ADG), average daily feed intake (ADFI) and gain to feed ratio (G:F) were calculated.

Book Title

117th International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork

Pages

345

Language

en

File Format

application/pdf

DOI

https://doi.org/10.31274/safepork-180809-668

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Jan 1st, 12:00 AM

Activity of Sangrovit® against Lawsonia intracellularis in grower pigs and its impact on gut physiology and host immunity

Maastricht, Netherlands

Sanguinarine, a quaternary benzophenanthridine alkaloid plant extract of Macleya cordata, has demonstrated to have anti-inflammatory, antimicrobial and immunomodulatory effect. It increases the availability of aromatic amino acids and decreases the levels of toxic biogenic amines. This study was aimed to evaluate the effect of Sangrovit® supplementation as compared to tylosin on growth performance, feed efficiency and Lawsonia intracellularis shedding in pigs, and to determine the effect of Sangrovit® on the immune system. A total of 24 pigs, four weeks-old challenged with Lawsonia intracellularis were randomly allocated to a treatment group (control non-supplemented, 40 g Sangrovit®/mton, 75 g Sangrovit®/mton, and 22g /kg tylosin). Pigs were weighed weekly and average daily gain (ADG), average daily feed intake (ADFI) and gain to feed ratio (G:F) were calculated.