Campus Units

Agronomy, Biochemistry, Biophysics and Molecular Biology, Roy J. Carver Department of, Electrical and Computer Engineering, Genetics, Development and Cell Biology, Statistics, Center for Plant Genomics

Document Type

Article

Publication Version

Published Version

Publication Date

11-20-2009

Journal or Book Title

Science

Volume

326

Issue

5956

First Page

1112

Last Page

1115

DOI

10.1126/science.1178534

Abstract

We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an important crop plant and model for biological research. Over 32,000 genes were predicted, of which 99.8% were placed on reference chromosomes. Nearly 85% of the genome is composed of hundreds of families of transposable elements, dispersed nonuniformly across the genome. These were responsible for the capture and amplification of numerous gene fragments and affect the composition, sizes, and positions of centromeres. We also report on the correlation of methylation-poor regions with Mu transposon insertions and recombination, and copy number variants with insertions and/or deletions, as well as how uneven gene losses between duplicated regions were involved in returning an ancient allotetraploid to a genetically diploid state. These analyses inform and set the stage for further investigations to improve our understanding of the domestication and agricultural improvements of maize.

Comments

This article is published as Schnable, Patrick S., Doreen Ware, Robert S. Fulton, Joshua C. Stein, Fusheng Wei, Shiran Pasternak, Chengzhi Liang et al. "The B73 maize genome: complexity, diversity, and dynamics." science 326, no. 5956 (2009): 1112-1115. doi: 10.1126/science.1178534.

Rights

Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.

Language

en

File Format

application/pdf

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