The results of this research suggest: (1) PRRSV has a detrimental effect on the uptake of copper particles by pulmonary intravascular macrophages (PIMs), (2) the severity of PRRSV-induced damage to PIMs differs among PRRSV isolates, and (3) PRRSV-induced decreased pulmonary clearance supports the hypothesis that PRRSV infection makes pigs more susceptible to bacterial septicemia.
Iowa State University
Thanawongnuwech, R.; Halbur, Patrick G.; Royer, R.; and Bruna, J., "PRRS Virus-Induced Damage to Intravascular Macrophages" (1998). Swine Research Report, 1997. 43.