Bacteriophage (phage) lysate was used for reducing the dissemination of Salmonella in pigs. The phage lysate was administrated into pigs beginning 1 hour after challenge for 2-hour duration. Three hours postchallenge, pigs were killed and necropsied. The numbers of Salmonella were enumerated in various tissue samples. Administration of the phage lysate lowered the numbers of Salmonella by 2 logs compared with controls in the colon and cecum contents. It suggests that use of phage could be considered as an alternative intervention strategy against Salmonella in pigs at the preharvest stage with further studies.
Iowa State University
Lee, N. and Harris, D.L. Hank, "Potential of bacteriophage application as an intervention strategy against Salmonella in pigs" (2003). Swine Research Report, 2002. 19.