Inactivation of the Caprine Arthritis-Encephalitis Virus Among Goat Populations by Colostrum.

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2014-04-15
Authors
Bohl, Aaron
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Symposium on Undergraduate Research and Creative Expression
Iowa State University Conferences and Symposia

The Symposium provides undergraduates from all academic disciplines with an opportunity to share their research with the university community and other guests through conference-style oral presentations. The Symposium represents part of a larger effort of Iowa State University to enhance, support, and celebrate undergraduate research activity.

Though coordinated by the University Honors Program, all undergraduate students are eligible and encouraged to participate in the Symposium. Undergraduates conducting research but not yet ready to present their work are encouraged to attend the Symposium to learn about the presentation process and students not currently involved in research are encouraged to attend the Symposium to learn about the broad range of undergraduate research activities that are taking place at ISU.

The first Symposium was held in April 2007. The 39 students who presented research and their mentors collectively represented all of ISU's Colleges: Agriculture and Life Sciences, Business, Design, Engineering, Human Sciences, Liberal Arts and Sciences, Veterinary Medicine, and the Graduate College. The event has grown to regularly include more than 100 students presenting on topics that span the broad range of disciplines studied at ISU.

Department
Veterinary Microbiology & Preventive Medicine
Abstract

The Caprine Arthritis-Encephalitis Virus (CAEV) is able to infect goats of all ages, breeds, and in all locations. It is particularly devastating to goat populations and represents a major economic problem for goat farming worldwide as goats are a major source of sustenance and trade among most of the world. Finding a way to effectively inactivate and immunize for CAEV is crucial to maintain healthy goat populations and prevent a potential global economic crash among goat farming. The most common way to inactivate CAEV is to perform heat treatment of colostrum however this may disrupt the anti-viral effects that colostrum naturally maintains. The Trujillo lab sets out to find better alternatives, if any, to treat the colostrum, or if the colostrum needs treated to kill CAEV at all. Studies done in lab have suggested that colostrum exhibits a very high efficiency of inactivating CAEV on its own and may not need treatment to pass on immunity. We test different strains of virus on colostrum and calculate a titer that will hopefully help us determine how effective colostrum is at inactivating CAEV and we also will perform a test by challenging live kids to determine the outcome.

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