Major(s)

Murphy: Biology; Meseck: Animal Science

Mentor(s)

Matthew Brewer

Department

Veterinary Pathology

Location

Memorial Union, South Ballroom

Session Title

Poster Presentations

Start Date

HH-11-4-2017

End Date

HH-11-4-2017

Description

Tritrichomonas foetus is a sexually-transmitted protozoan parasite infecting cattle throughout the world. In cows, infection results in early embryonic death and abortion. Current control methods rely on culling infected animals and there is no curative treatment. We obtained a field strain of the parasite from an Iowa bull and isolated it in axenic culture. We then developed a trophozoite killing assay suitable for identifying compounds with anti-parasite activity. Current and future studies involve screening of antimicrobial agents and identification of lead compounds for future in vivo studies.

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Apr 11th, 3:00 PM Apr 11th, 5:00 PM

Trophozoite killing assays for Tritrichomonas foetus parasites

Memorial Union, South Ballroom

Tritrichomonas foetus is a sexually-transmitted protozoan parasite infecting cattle throughout the world. In cows, infection results in early embryonic death and abortion. Current control methods rely on culling infected animals and there is no curative treatment. We obtained a field strain of the parasite from an Iowa bull and isolated it in axenic culture. We then developed a trophozoite killing assay suitable for identifying compounds with anti-parasite activity. Current and future studies involve screening of antimicrobial agents and identification of lead compounds for future in vivo studies.