Campus Units
Veterinary Clinical Sciences, Veterinary Diagnostic and Production Animal Medicine
Document Type
Article
Publication Version
Published Version
Publication Date
2-2017
Journal or Book Title
American Journal of Veterinary Research
Volume
78
Issue
2
First Page
230
Last Page
238
DOI
10.2460/ajvr.78.2.230
Abstract
OBJECTIVE To assess multiple central venous and arterial blood variables that alone o r in conjunction with one another reflect global oxygenation status in healthy neonatal foals.
ANIMALS 11 healthy neonatal foals.
PROCEDURES Central venous and arterial blood samples were collected from healthy neonatal foals at 12, 24, 36, 48, 72, and 96 hours after birth. Variables measured from central venous and arterial blood samples included oxygen saturation of hemoglobin, partial pressure of oxygen, lactate concentration, partial pressure of carbon dioxide, and pH. Calculated variables included venous-to-arterial carbon dioxide gap, estimated oxygen ext raction ratio, ratio of partial pressure of oxygen in arterial blood to the fraction of inspired oxygen, bicarbonate concentration, base excess, and blood oxygen content.
RESULTS Significant differences between arterial and central venous blood obtained from neonatal foals were detected for several variables, particularly partial pressure of oxygen, oxygen saturation of hemoglobin, and oxygen content. In addition, the partial pressure of carbon dioxide in central venous blood samples was significantly higher than the value for cor responding arterial blood samples. Several temporal differences were detected for other variables.
CONCLUSIONS AND CLINICAL RELEVANCE Results of this study provided info rmation about several variables that reflect global oxygenation in healthy neonatal foals. Values for these variables in healthy foals can allow for comparison with values for critically ill foals in future studies. Comparison of these variables between healthy and ill foals may aid in treatment decisions and prognosis of clinical outcome for crit ically ill foals.
Copyright Owner
American Veterinary Medical Association
Copyright Date
2017
Language
en
File Format
application/pdf
Recommended Citation
Wong, David M.; Hepworth-Warren, Kate L.; Sponseller, Beatrice T.; Howard, Joan M.; and Wang, Chong, "Measured and calculated variables of global oxygenation in healthy neonatal foals" (2017). Veterinary Diagnostic and Production Animal Medicine Publications. 116.
https://lib.dr.iastate.edu/vdpam_pubs/116
Included in
Large or Food Animal and Equine Medicine Commons, Veterinary Physiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons
Comments
This article is published as Wong, David M., Kate L. Hepworth-Warren, Beatrice T. Sponseller, Joan M. Howard, and Chong Wang. "Measured and calculated variables of global oxygenation in healthy neonatal foals." American journal of veterinary research 78, no. 2 (2017): 230-238. doi: 10.2460/ajvr.78.2.230. Posted with permission.