Campus Units
Veterinary Diagnostic and Production Animal Medicine, Statistics, Veterinary Clinical Sciences
Document Type
Article
Publication Version
Published Version
Publication Date
2010
Journal or Book Title
American Journal of Veterinary Research
Volume
71
Issue
9
First Page
1081
Last Page
1088
DOI
10.2460/ajvr.71.9.1081
Abstract
Objective—To evaluate the effects of various flow rates of oxygen administered via 1 or 2 nasal cannulae on the fraction of inspired oxygen concentration (Fio2) and other arterial blood gas variables in healthy neonatal foals.
Animals—9 healthy neonatal (3- to 4-day-old) foals.
Procedures—In each foal, a nasal cannula was introduced into each naris and passed into the nasopharynx to the level of the medial canthus of each eye; oxygen was administered at 4 flow rates through either 1 or both cannulae (8 treatments/foal). Intratracheal Fio2, intratracheal end-tidal partial pressure of carbon dioxide, and arterial blood gas variables were measured before (baseline) and during unilateral and bilateral nasopharyngeal delivery of 50, 100, 150, and 200 mL of oxygen/kg/min.
Results—No adverse reactions were associated with administration of supplemental oxygen except at the highest flow rate, at which the foals became agitated. At individual flow rates, significant and dose-dependent increases in Fio2, Pao2, and oxygen saturation of hemoglobin (Sao2) were detected, compared with baseline values. Comparison of unilateral and bilateral delivery of oxygen at similar cumulative flow rates revealed no differences in evaluated variables.
Conclusions and Clinical Relevance—Results indicated that administration of supplemental oxygen via nasal cannulae appeared to be a highly effective means of increasing Fio2, Pao2, and Sao2 in neonatal foals. These findings may provide guidance for implementation of oxygen treatment in hypoxemic neonatal foals.
Copyright Owner
American Veterinary Medical Association
Copyright Date
2010
Language
en
File Format
application/pdf
Recommended Citation
Wong, David M.; Alcott, Cody J.; Wang, Chong; Hay-Kraus, Bonnie L.; Buchanan, Benjamin R.; and Brockus, Charles W., "Physiologic effects of nasopharyngeal administration of supplemental oxygen at various flow rates in healthy neonatal foals" (2010). Veterinary Diagnostic and Production Animal Medicine Publications. 77.
https://lib.dr.iastate.edu/vdpam_pubs/77
Included in
Large or Food Animal and Equine Medicine Commons, Statistical Methodology Commons, Veterinary Physiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons
Comments
This article is from American Journal of Veterinary Research 71 (2010): 1081, doi: 10.2460/ajvr.71.9.1081. Posted with permission.