Campus Units

Veterinary Microbiology and Preventive Medicine

Document Type

Article

Publication Version

Published Version

Publication Date

10-2015

Journal or Book Title

Antimicrobial Agents and Chemotherapy

Volume

59

Issue

10

First Page

6661

Last Page

6664

DOI

10.1128/AAC.01103-15

Abstract

Macrolides are the antimicrobials of choice for treating human campylobacteriosis. The recent emergence of erm(B) in Campylobacter bacteria threatens the utility of this class of antibiotics. Here we report the constitutive and inducible expression of erm(B) in Campylobacter isolates derived from diarrheal patients and food-producing animals. Constitutive expression of erm(B) was associated with insertion and deletion in the regulatory region of the gene, providing the first documentation of the differential expression of erm(B) in Campylobacter bacteria.

Comments

This article is published as Deng, Fengru, Jianzhong Shen, Maojun Zhang, Congming Wu, Qijing Zhang, and Yang Wang. "Constitutive and inducible expression of the rRNA methylase gene erm (B) in Campylobacter." Antimicrobial agents and chemotherapy 59, no. 10 (2015): 6661-6664. doi: 10.1128/AAC.01103-15. Posted with permission.

Copyright Owner

American Society for Microbiology

Language

en

File Format

application/pdf

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