Campus Units

Veterinary Microbiology and Preventive Medicine

Document Type

Article

Publication Version

Published Version

Publication Date

1-1984

Journal or Book Title

Infection and Immunity

Volume

43

Issue

1

First Page

66

Last Page

71

Abstract

The effect of various Pasteurella multocida fractions on bovine polymorphonuclear leukocyte (PMN) functions was examined in vitro by using two encapsulated strains, P-2383 and P-1062 (both are Carter capsular type A and of bovine origin). The ability of PMNs to ingest Staphylococcus aureus and iodinate protein was significantly inhibited in the presence of live cells, heat-killed whole cells, or saline-extracted capsules but not in the presence of the decapsulated heat-killed cells. None of the fractions of the two strains inhibited nitroblue tetrazolium reduction by PMNs. The saline extract did not inhibit the binding of iodine to protein by a reaction involving xanthine, xanthine oxidase, and horseradish peroxidase. The PMN inhibitory factor was further characterized as a heat-stable capsular material of greater than 300,000 molecular weight.

Comments

This article is published as Ryu, Hyoik, Merlin L. Kaeberle, James A. Roth, and Ronald W. Griffith. "Effect of type A Pasteurella multocida fractions on bovine polymorphonuclear leukocyte functions." Infection and immunity 43, no. 1 (1984): 66-71. Posted with permission.

Copyright Owner

American Society for Microbiology

Language

en

File Format

application/pdf

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