Veterinary Microbiology and Preventive Medicine
Journal or Book Title
American Journal of Veterinary Research
Neutrophils from 8 Holstein heifers were evaluated for function during the periparturient period. Random migration, ingestion of bacteria, superoxide anion production, native (nonenhanced) chemiluminescence, iodination, and antibody-dependent, cell-mediated cytotoxicity by neutrophils were determined. Foremilk samples were evaluated for bacteria. Significant (P < 0.05) increases in random migration of neutrophils, iodination, and chemiluminescence were evident 2 weeks before parturition and then decreased dramatically by the frrst week after parturition. These impairments of neutrophil function after parturition may be manifested as a severe cumulative deficit in the native defenses afforded by the neutrophil.
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
Kehrli, Marcus E.; Nonnecke, Brian J.; and Roth, James A., "Alterations in bovine neutrophil function during the periparturient period" (1989). Veterinary Microbiology and Preventive Medicine Publications. 191.
Large or Food Animal and Equine Medicine Commons, Veterinary Microbiology and Immunobiology Commons, Veterinary Pathology and Pathobiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons