Campus Units
Veterinary Microbiology and Preventive Medicine
Document Type
Article
Publication Version
Published Version
Publication Date
7-1993
Journal or Book Title
Journal of Virology
Volume
67
Issue
7
First Page
4399
Last Page
4403
Abstract
Transient expression assays using the reporter gene that encodes chloramphenicol acetyltransferase were used to identify cis-acting sequences necessary for bovine immunodeficiency-like virus (BIV) transactivation. Computer analyses identified two RNA stem-loop structures located immediately downstream of the transcription start site in the long terminal repeat. Deletion analysis of the long terminal repeat indicated that sequences containing the proximal stem-loop structure located between +4 and +31 are required for virus-specific transactivation. Therefore, BIV likely utilizes a mechanism of transactivation similar to that of the human and simian lentiviruses.
Copyright Owner
American Society for Microbiology
Copyright Date
1993
Language
en
File Format
application/pdf
Recommended Citation
Carpenter, Susan; Nadin-Davis, Susan A.; Wannemuehler, Yvonne; and Roth, James A., "Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus" (1993). Veterinary Microbiology and Preventive Medicine Publications. 195.
https://lib.dr.iastate.edu/vmpm_pubs/195
Included in
Genetics Commons, Veterinary Infectious Diseases Commons, Veterinary Microbiology and Immunobiology Commons, Veterinary Pathology and Pathobiology Commons, Veterinary Preventive Medicine, Epidemiology, and Public Health Commons
Comments
This article is published as Carpenter, S., S. A. Nadin-Davis, Y. Wannemuehler, and J. A. Roth. "Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus." Journal of virology 67, no. 7 (1993): 4399-4403. Posted with permission.