Veterinary Microbiology and Preventive Medicine
Journal or Book Title
Journal of Virology
Transient expression assays using the reporter gene that encodes chloramphenicol acetyltransferase were used to identify cis-acting sequences necessary for bovine immunodeficiency-like virus (BIV) transactivation. Computer analyses identified two RNA stem-loop structures located immediately downstream of the transcription start site in the long terminal repeat. Deletion analysis of the long terminal repeat indicated that sequences containing the proximal stem-loop structure located between +4 and +31 are required for virus-specific transactivation. Therefore, BIV likely utilizes a mechanism of transactivation similar to that of the human and simian lentiviruses.
American Society for Microbiology
Carpenter, Susan; Nadin-Davis, Susan A.; Wannemuehler, Yvonne; and Roth, James A., "Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus" (1993). Veterinary Microbiology and Preventive Medicine Publications. 195.
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