The pap Operon of Avian Pathogenic Escherichia coli Strain O1:K1 Is Located on a Novel Pathogenicity Island
Date
2006-01-01
Authors
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Authors
Person
Nolan, Lisa
Professor Emeritus
Research Projects
Organizational Units
Organizational Unit
Veterinary Microbiology and Preventive Medicine
Our faculty promote the understanding of causes of infectious disease in animals and the mechanisms by which diseases develop at the organismal, cellular and molecular levels. Veterinary microbiology also includes research on the interaction of pathogenic and symbiotic microbes with their hosts and the host response to infection.
Journal Issue
Is Version Of
Versions
Series
Department
Veterinary Microbiology and Preventive Medicine
Abstract
We have identified a 56-kb pathogenicity island (PAI) in avian pathogenicEscherichia coli strain O1:K1 (APEC-O1). This PAI, termed PAI IAPEC-O1, is integrated adjacent to the 3′ end of the pheV tRNA gene. It carries putative virulence genes of APEC (pap operon), other E. coli genes (tia and ireA), and a 1.5-kb region unique to APEC-O1. The kps gene cluster required for the biosynthesis of polysialic acid capsule was mapped to a location immediately downstream of this PAI.
Comments
This article is from Infection and Immunity 74, no. 1 (January 2006): 744–749, doi:10.1128/IAI.74.1.744-749.2006.
Description
Keywords
Citation
DOI
Copyright
Sun Jan 01 00:00:00 UTC 2006