Document Type

Article

Publication Date

1999

Journal or Book Title

Avian Diseases

Volume

43

Issue

4

First Page

656

Last Page

663

DOI

10.2307/1592734

Abstract

As a feed additive, ascorbic acid has been shown to have a protective effect against bacterial and viral diseases and to reduce the impact of detrimental stress in chickens. This study examined the effect of ascorbic acid treatment on in vitro heterophil function by examining random migration and phagocytosisa nd bacterialk illing of Staphylococcuasu reus. Heterophils were evaluated in broiler chickens ranging from 5 to 16 wk of age, and age differences were seen. Significant increases in bacterial killing were found in heterophils treated with ascorbic acid, and this difference tended to be greater in chickens from 5 to 10.5 wk of age. No significant differences were found in phagocytosis or random migration, but ascorbic acid tended to decrease random migration. The most significant effect on in vitro heterophil function was an increase in bacterial killing.

Comments

This article is from Avian Diseases 43 (1999): 656-663, doi:10.2307/1592734. Posted with permission.

Copyright Owner

American Association of Avian Pathologists

Language

en

File Format

application-pdf

Share

COinS