Campus Units

Veterinary Pathology

Document Type

Article

Publication Version

Published Version

Publication Date

1995

Journal or Book Title

Avian Diseases

Volume

39

Issue

2

First Page

328

Last Page

336

DOI

10.2307/1591875

Abstract

In three separate experiments, 2- or 5-day-old commercial turkey poults were inoculated orally with astrovirus and examined for clinical signs and for gross and microscopic lesions over a period of 14 days. By day 2 postinoculation (PI), inoculated poults had de- veloped diarrhea, generalized loss of intestinal tone, and dilated ceca that contained light- yellow fluid feces and gas; these changes persisted through day 10 PI. Mild crypt hyperplasia was the only change discernible by light microscopy, and it was first noted in the proximal jejunum on day 1 PI, in the distal jejunum and ileum on day 3 PI, and in the duodenum on day 5 PI. A significant (P < 0.05) increase in crypt depth and area was documented by image analysis on day 3 PI. Ultrastructural evaluation revealed intracytoplasmic aggregates of astro- virus in enterocytes on the sides and base of villi in the ileum and distal jejunum on day 3 PI. Based on the findings, it was concluded that astrovirus caused lesions and replicated in both upper and lower segments of the small intestine in turkey poults.

Comments

This article is published as Thouvenelle, Mari L., Joseph S. Haynes, and Don L. Reynolds. "Astrovirus infection in hatchling turkeys: histologic, morphometric, and ultrastructural findings." Avian diseases (1995): 328-336. doi: 10.2307/1591875. Posted with permission.

Copyright Owner

American Association of Avian Pathologists

Language

en

File Format

application/pdf

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