Campus Units

Veterinary Pathology, Animal Science

Document Type

Article

Publication Version

Published Version

Publication Date

1995

Journal or Book Title

Avian Diseases

Volume

39

Issue

2

First Page

343

Last Page

348

DOI

10.2307/1591877

Abstract

Two experiments were conducted to determine intestinal disaccharidase ac- tivity in 1-day-old commercial turkey poults inoculated with astrovirus. Small intestinal sam- ples were collected on days 0.5, 1, 3, and 7 postinoculation (PI) in Expt. 1 and on days 7, 10, and 14 PI in Expt. 2 and evaluated for specific maltase activity (SMA). Astrovirus infection was verified on day 7 PI by immune electron microscopy of intestinal contents. Inoculated poults developed diarrhea and a transient, significant decrease in intestinal SMA. SMA was significantly (P < 0.05) lower in astrovirus-inoculated poults than in control poults throughout the entire small intestine from day 3 through day 7 PI. However, SMA had returned to normal in inoculated poults by day 10 PI and was significantly higher than control values (P < 0.05) in all sections of the small intestine, except in the proximal jejunum, by day 14 PI. Decreased SMA caused by astrovirus infection resulted in disaccharide maldigestion, mal- absorption, and subsequent osmotic diarrhea. As astrovirus was cleared from the intestinal tract, SMA was restored and diarrhea was resolved.

Comments

Thouvenelle, Mari L., Joseph S. Haynes, Jerry L. Sell, and Don L. Reynolds. "Astrovirus infection in hatchling turkeys: alterations in intestinal maltase activity." Avian diseases (1995): 343-348. doi: 10.2307/1591877. Posted with permission.

Copyright Owner

American Association of Avian Pathologists

Language

en

File Format

application/pdf

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